Validation of an enzyme-linked immunosorbent assay that detects Histoplasma capsulatum antigenuria in colombian patients with AIDS for diagnosis and follow-up during therapy
Artículo académico
We validated an antigen capture enzyme-linked immunosorbent assay (ELISA) in Colombian persons with AIDS and proven histoplasmosis and evaluated the correlation between antigenuria and clinical improvement during follow-up. The sensitivity of the Histoplasma capsulatum ELISA was 86%, and the overall specificity was 94%. The antigen test successfully monitored the response to therapy.
