Cerebral autoregulation assessment in premature infants: clinical relevance
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Abstracto
Cerebral auto-regulation was assessed in premature infants by the analysis of the common dynamics between the Cerebral Blood Flow (CBF) and Mean Arterial Blood Pressure (MABP). Changes in cerebral intravascular oxygenation (HbD), regional cerebral oxygen saturation (rSO2), and cerebral tissue oxygenation (TOI), all recorded with Near-Infrared Spectroscopy (NIRS), were used as an indirect measurement that reflects changes in CBF. Correlation,(partial) coherence and transfer function analysis scores were compared with normal and abnormal population in order to establish the importance of cerebral auto-regulation in clinical practice.